1H-Pyrazole, 3-(chloromethyl)-1-ethyl- - Names and Identifiers
1H-Pyrazole, 3-(chloromethyl)-1-ethyl- - Physico-chemical Properties
Molecular Formula | C6H9ClN2
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Molar Mass | 144.6 |
Density | 1.16±0.1 g/cm3(Predicted) |
Boling Point | 229.4±15.0 °C(Predicted) |
pKa | 1.33±0.10(Predicted) |
Storage Condition | Room Temprature |
Sensitive | IRRITANT |
MDL | MFCD09834155 |
1H-Pyrazole, 3-(chloromethyl)-1-ethyl- - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 41 - Risk of serious damage to eyes
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
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1H-Pyrazole, 3-(chloromethyl)-1-ethyl- - Introduction
3-(Chloromethyl)-1-ethyl-1H-pyrazole is an organic compound whose chemical formula is C7H9ClN2. The following is a description of some properties, uses, preparation and safety information about this compound:
Nature:
-Appearance: 3-(Chloromethyl)-1-ethyl-1H-pyrazole is a colorless to light yellow liquid.
-Melting point: Its melting point is about -17°C to -20°C.
-Boiling point: Its boiling point is approximately 131°C to 133°C.
-Solubility: 3-(Chloromethyl)-1-ethyl-1H-pyrazole is soluble in many organic solvents.
Use:
-Pharmaceutical field: 3-(Chloromethyl)-1-ethyl-1H-pyrazole is an intermediate compound that can be used to synthesize various drugs and biologically active molecules. For example, it can be used in the preparation of antiviral, antitumor and anti-inflammatory drugs, etc.
Preparation Method:
- 3-(Chloromethyl)-1-ethyl-1H-pyrazole is usually synthesized by the following steps:
1.3-(chloromethyl)-1-pyrazole methanol was obtained from pyrazole and chloromethanol.
2.3-(chloromethyl)-1-pyrazole methanol reacts with iodoethane to generate 3-(Chloromethyl)-1-ethyl-1H-pyrazole.
Safety Information:
- 3-(Chloromethyl)-1-ethyl-1H-pyrazole is irritating to the skin and eyes, and should be rinsed with water immediately after contact.
-Avoid inhaling gases, vapors, spray or dust during use.
-Wear appropriate personal protective equipment such as goggles, gloves and protective clothing during operation.
-The compound should be stored in a sealed container, away from fire and oxidizing agents.
-When using and handling, follow relevant safety operating procedures and pay attention to ventilation to prevent inhalation.
Please note that the above information is for reference only. When using 3-(Chloromethyl)-1-ethyl-1H-pyrazole, refer to accurate chemical safety data and follow laboratory safe operating procedures.
Last Update:2024-04-09 15:18:09